Explore the Agenda
8:00 am Morning Coffee and Check-in
8:55 am Chair’s Opening Remarks
The Expanding Potential of Nose-to-Brain Delivery to Unlock CNS Access and Transform Therapeutic Impact
9:00 am Overcoming Anatomical & Physiological Barriers to Enable Reliable Olfactory and Trigeminal Uptake
Explore challenges in delivering drugs to the olfactory region and trigeminal pathways with high precision
- Review strategies to navigate the nasal cavity for consistent CNS targeting
- Case studies highlighting successful intranasal delivery
- Current models to test olfactory delivery where are the gaps and the innovations?
9:30 am Enhancing CNS Targeting Efficiency to Maximise Therapeutic Impact Through Novel Approaches
- Explore emerging formulation and device strategies that increase direct brain uptake of drugs and biologics
- Understand approaches to minimize systemic exposure while maximizing CNS delivery for better efficacy and safety
- Gain insights into experimental and translational methods that can accelerate the development of CNS-targeted therapies
10:00 am Morning Break & Speed Networking
The ideal opportunity to get face-to-face with many global nasal formulation and delivery leaders for important in-depth conversations.
Future-Proofing Commercial Viability & Intranasal Market Readiness to Accelerate Successful Product Launches
11:00 am Designing Device & Contract Manufacturing Considerations to Enable Scalable and Commercially Viable Intranasal Products
- Understand the critical difference between producing batches for early studies versus large-scale commercial production.
- Learn how to assess partner capabilities, capital readiness and long-term vision to ensure they can support commercialization, not just development
- Explore strategies to align device design, manufacturing investment and regulatory timelines when capital and resources are constrained
11:30 am Session Reserved for Aptar
12:00 pm Panel Session: Successes and Failures in Nasal Drug Delivery to Learn Best Practices
- Review successes and failures in bringing intranasal drugs from concept to commercialization
- Examine strategies for driving adoption, demonstrating clinical value, and overcoming market inertia
- Learn practical tactics for optimizing launch timing, pricing, and market positioning
12:45 pm Lunch Break & Networking
The Critical Formulation Challenges Limiting Intranasal Performance and the Innovations Needed to Overcome Them
1:45 pm Overcoming Solubility, Stability & Viscosity Barriers to Achieve Reliable Nasal Absorption and Unlock Therapeutic-Level Dosing
- Explore approaches to solubilize and stabilize small molecules, biologics, and nucleic acids within limited nasal volumes
- Understand how viscosity and excipient selection impact dissolution, absorption, and formulation performance
- Discuss formulation design strategies to maximise therapeutic levels while maintaining patient safety
2:15 pm Tackling Mucoadhesion, Mucociliary Clearance & Nasal Residence Time for Improved Therapeutic Uptake
- Examine strategies to modulate mucoadhesion and overcome rapid clearance by the nasal mucosa
- Explore delivery approaches to optimize deposition and retention in target regions of the nasal cavity
- Learn how formulation-device integration can improve residence time and therapeutic outcomes
2:45 pm Session Reserved for Kindeva
3:15 pm Afternoon Break & Poster Session
Witness some of the latest and greatest research in the nasal drug development & delivery field by drug developers, academics, service providers, and researchers in this spotlight poster session!
Optimizing Drug–Device Compatibility to Maximize Nasal Delivery Performance and Therapeutic Effectiveness
4:00 pm GW-TT2: Achieving Reliable Nasal Delivery of Hydrophobic Drugs Through Formulation–Device Alignment
- Explore the impact of various formulation attributes on CNS and inner ear targeting
- Understand challenges in low-dose delivery and strategies to prevent underdosing
- Case study examples from a unique nasal formulation and delivery relief to recent onset tinnitus
4:30 pm Exploring Powder-Based Intranasal Delivery as a Platform for Systemic Therapeutics
- Compare powder versus liquid intranasal delivery, highlighting how deeper nasal deposition, increased surface area, and richer vascular access can drive faster and higher systemic absorption
- Explore the critical challenges of particle size distribution, particle shape, and limited large-scale manufacturing capacity, and how proprietary formulation strategies can address them
- Advancing powder-based naloxone and epinephrine programs, including device considerations, scalability planning, and where innovation is still needed across delivery technologies and manufacturing infrastructure