Understanding Anatomical Variability & Its Impact on Intranasal Drug Delivery
4:00 pm - Wednesday 3rd February 2027
- Address the challenge of highly variable patient anatomy by understanding how differences in nasal geometry, airflow patterns, and target site accessibility can influence deposition, absorption, and therapeutic outcomes
- Evaluate the impact of common factors such as nasal obstruction, congestion, inflammation, and disease state on delivery performance to improve study design and patient selection strategies
- Improve confidence in clinical translation by identifying approaches to account for anatomical variability during preclinical development, device optimization, and clinical evaluation to achieve more consistent treatment outcomes across patient populations